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It’s not uncommon to feel disorganized and forgetful when you’re under a lot of stress. But over the long term, stress may actually change your brain in ways that affect your memory. Studies in both animals and...
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has...
A new commentary by scientists at the Universities of Manchester and Edinburgh on a study by Taiwanese epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer’s disease. When the Taiwanese authors...
Sex differences in dementia are only just being recognized – but the consequences could change the way we fight the disease. Diagnosed with Alzheimer’s in 2015, 75-year-old Brenda Whittle still enjoys jigsaws, sewing and dancing....
Scientists have discovered a “Big Bang” of Alzheimer’s disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain. A study from UT Southwestern’s O’Donnell Brain...
Driven by the urgent need for effective new treatments for dementia, deep brain stimulation (DBS) is being studied as a potential therapy to improve cognition and memory, or delay decline – and it is showing...
For more than 20 years, much of the leading research on Alzheimer’s disease has been guided by the “amyloid hypothesis.” This theory focuses on one of the disease’s most salient traits – the formation...
New findings from the long-running Whitehall II study of over 10,000 civil servants has found 50-year-olds who had blood pressure that was higher than normal but still below the threshold commonly used when deciding to treat the...
Multiple genes are implicated in Alzheimer’s disease. Some are linked to early-onset Alzheimer’s, a condition that develops in one’s 30s, 40s and 50s, while others are associated with the more common late-onset form...
A recent study examines the association between alcohol consumption and the progression of Alzheimer’s disease. Research from the University of Illinois at Chicago found that some of the genes affected by alcohol and inflammation are also implicated...
People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease. APOE4 is three times more common among Alzheimer’s patients than it is among the general population. However, little is...
Ever had a ‘gut feeling’ about something? It turns out the connection between our gut and our brain might be stronger than we think. Research led by John F Cryan and Ted Dinan at APC Microbiome Ireland has...
A study analyzing the DNA of more than 300,000 individuals has uncovered three new genes associated with Alzheimer’s disease. Two of the genes are already targeted by drugs used to treat other conditions, paving...
Women showed a stronger association between the apolipoprotein E (APOE) gene and cerebrospinal fluid (CSF) tau levels than men, particularly if they were amyloid-positive, researchers reported. However, in the meta-analysis of 10 longitudinal studies...
Body-worn sensors used at home and in clinic by people with mild Alzheimer’s to assess walking could offer a cost-effective way to detect early disease and monitor progression of the illness. A pilot study involving Newcastle University,...
A Western-style diet triggers changes in the brain that may predispose patients to Alzheimer’s disease decades before they show any sign of cognitive decline, according to new research by Weill Cornell Medicine investigators. In two studies,...
A recent comprehensive review on the use of fMRI sought to evaluate the robustness and effectiveness of this approach for studying Alzheimer’s patients. Alzheimer’s disease is the most common neurodegenerative disorder and is...
The hormone insulin, administered via a nasal spray, is being investigated as a treatment for Alzheimer’s disease. While insulin is best known for its role in regulating blood sugar, it also is thought to...
Scientists in California successfully changed a protein associated with Alzheimer’s disease into a more harmless form, allowing them to erase brain cell damage. The breakthrough is especially important because the research was not conducted on...
The hippocampus is an area of the brain commonly linked with memory and dementia. But new U of T Scarborough research finds that it may also yield important clues about a range of mental...
here is, as yet, no cure for Alzheimer’s disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for...
Contrary to popular thought, older adults’ brains can churn out just as many new cells as younger brains do, a new study suggests. Using autopsied brain tissue, researchers found that healthy older adults had the...
A Vancouver-based research team led by Canada’s most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent...
In asymptomatic women and carriers of apolipoprotein E ε4 (APOE ε4) who have a parental history of Alzheimer disease (AD) dementia, the proximity to parental age at symptom onset may identify amyloid-β (Aβ) biomarker...
