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A hallmark of Alzheimer’s disease is the accumulation of amyloid-β (Aβ) peptide. Donanemab, an antibody that targets a modified form of deposited Aβ, is being investigated for the treatment of early Alzheimer’s disease. A phase...
New research from the University of Sheffield has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer’s disease. The pioneering multimodal neuroimaging study revealed obesity may contribute toward neural tissue...
Sex and gender differences seem to play a role in the individuals’ psychological and behavioral reactions to the COVID-19 pandemic. These differences need to be considered in planning targeted psychological interventions. Although effective in...
A genetic variation in some people may be associated with cognitive decline that can’t be explained by deposits of two key proteins associated with Alzheimer’s disease, amyloid β and tau, according to a study...
Estrogen therapy is commonly prescribed by physicians to transgender women who chose to undergo gender confirmation surgery(ies). Estrogens are a versatile group of hormones with a variety of roles in the human body, one...
Controlling blood sugar levels improved the ability to clearly think, learn and remember among people with type 2 diabetes who were overweight, a new study shows. But losing weight, especially for people who were obese,...
As a group, women may be more likely than men to develop Alzheimer’s disease, but once they have it, they cope better and live longer. A study published August 26 in Science Translational Medicine credits...
Although it’s normal for brainpower to decline as people age, it’s not inevitable, studies show. Some people remain cognitively sharp into their 80s, 90s, and beyond, defying the common assumption that cognitive decline is a...
The number of older people, including those living with dementia, is rising, as younger age mortality declines. However, the age-specific incidence of dementia has fallen in many countries, probably because of improvements in education, nutrition, health...
Researchers believe game-changing test will be available to doctors in two years. A simple blood test may be able to tell you whether you have Alzheimer’s disease and, in some cases, it can detect the...
At least one flu vaccination was associated with a 17% reduction in Alzheimer’s incidence. More frequent flu vaccination was associated with another 13% reduction in Alzheimer’s incidence. Vaccination against pneumonia...
A new study published in the International Journal of Environmental Research and Public Health found that roughly 45 minutes of vigorous exercise during the pandemic sufficiently reduced negative emotions in a sample of Chinese college students. Strict...
Alzheimer’s disease does discriminate when it comes to gender. Two-thirds of all cases are women, and in the past it was believed that this was because women tend to live longer than men. However, a...
Obesity is associated with a higher risk of dementia up to 15 years later, finds a new UCL study suggesting that weight management could play a significant role in reducing risk. The findings, published in the International...
Even among healthy people, a faltering memory is often an expected part of aging – but it’s not inevitable. “Some individuals exhibit remarkable maintenance of memory function throughout late adulthood, whereas others experience significant...
In the 21st century, global health has seen a drastic shift in the incidence of diseases affecting the human population. In early 2000, the World Health Organization (WHO) reported the top 10 global...
Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory. But what happens during exercise to trigger these benefits? New UT Southwestern research that mapped...
The earlier we can diagnose Alzheimer’s, the better. This is why scientists are putting so much focus on the human eye. While the exact link between the eye and Alzheimer’s disease is still occluded,...
It’s never too late to lace up some sneakers and work up a sweat for brain health, according to a study published in the May 13, 2020, online issue of Neurology, the medical journal of the...
More evidence that one of the reasons why more women than men might have Alzheimer’s disease is because of early life endocrine changes. Oophorectomy prior to menopause is associated with...
Stanford Medicine researchers have found a gene variant that protects carriers of another gene variant, ApoE4, from developing Alzheimer’s disease — the first demonstration of that beneficial effect. People with a gene variant that puts them at...
Alzheimer’s disease has long been characterized primarily by the buildup of two proteins in the brain – beta-amyloid and tau. Decades of focus on beta-amyloid has failed to significantly help patients. So researchers are...
Advanced age is the most significant risk factor for late-onset Alzheimer’s disease, and having a parent with the disease is the second. It is estimated that individuals with a first-degree relative with Alzheimer’s disease (AD)...
A team of researchers, led by NYU Abu Dhabi Assistant Professor of Biology Mazin Magzoub, has developed small proteins called cell-penetrating peptides (CPPs) that prevent the aggregation of the amyloid-β (Aβ) protein associated with Alzheimer’s disease....
