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Psychobiotics – Our gut and our brain connection might be stronger than we think

Ever had a ‘gut feeling’ about something? It turns out the connection between our gut and our brain might be stronger than we think. Research led by John F Cryan and Ted Dinan at APC Microbiome Ireland has...

3 New Genes Linked to Alzheimer’s Disease

A study analyzing the DNA of more than 300,000 individuals has uncovered three new genes associated with Alzheimer’s disease. Two of the genes are already targeted by drugs used to treat other conditions, paving...

Alzheimer’s Link Between APOE, Tau Stronger in Women

Women showed a stronger association between the apolipoprotein E (APOE) gene and cerebrospinal fluid (CSF) tau levels than men, particularly if they were amyloid-positive, researchers reported. However, in the meta-analysis of 10 longitudinal studies...

Gait assessed with body-worn sensors may help detect onset of Alzheimer’s

Body-worn sensors used at home and in clinic by people with mild Alzheimer’s to assess walking could offer a cost-effective way to detect early disease and monitor progression of the illness. A pilot study involving Newcastle University,...

Mediterranean Diet May Protect Against Alzheimer’s

A Western-style diet triggers changes in the brain that may predispose patients to Alzheimer’s disease decades before they show any sign of cognitive decline, according to new research by Weill Cornell Medicine investigators. In two studies,...

Using fMRI to track Alzheimer’s treatments

A recent comprehensive review on the use of fMRI sought to evaluate the robustness and effectiveness of this approach for studying Alzheimer’s patients. Alzheimer’s disease is the most common neurodegenerative disorder and is...

Nasal Insulin as a Possible Alzheimer’s Treatment

The hormone insulin, administered via a nasal spray, is being investigated as a treatment for Alzheimer’s disease. While insulin is best known for its role in regulating blood sugar, it also is thought to...

ALZHEIMER’S DAMAGE COULD BE ERASED BY CHANGING STRUCTURE OF ONE PROTEIN

Scientists in California successfully changed a protein associated with Alzheimer’s disease into a more harmless form, allowing them to erase brain cell damage. The breakthrough is especially important because the research was not conducted on...

Memory part of the brain may also hold clues for anxiety and depression

The hippocampus is an area of the brain commonly linked with memory and dementia. But new U of T Scarborough research finds that it may also yield important clues about a range of mental...

New blood test useful to detect people at risk of developing Alzheimer’s

here is, as yet, no cure for Alzheimer’s disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for...

Older Brains Replenish Cells Just Like Young Brains

Contrary to popular thought, older adults’ brains can churn out just as many new cells as younger brains do, a new study suggests. Using autopsied brain tissue, researchers found that healthy older adults had the...

Could a daily dose of Ibuprofen ward off Alzheimer’s?

A Vancouver-based research team led by Canada’s most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent...

Assessing Parental Symptom Onset Proximity in Alzheimer’s

In asymptomatic women and carriers of apolipoprotein E ε4 (APOE ε4) who have a parental history of Alzheimer disease (AD) dementia, the proximity to parental age at symptom onset may identify amyloid-β (Aβ) biomarker...

Disrupted sleep-wake cycle might be measure for preclinical Alzheimer’s

People with dementia due to Alzheimer’s disease are known to have disrupted sleep. New NIH-funded research, published online Jan. 29, 2018, in JAMA Neurology, links a disrupted sleep-wake cycle to an earlier,...

Opioid analgesics reduce use of antipsychotics in persons with Alzheimer’s

Initiating an opioid analgesic reduced the use of antipsychotics and benzodiazepines in persons with Alzheimer’s disease, a recent study from the University of Eastern Finland shows. These drugs are frequently prescribed to treat behavioural and psychiatric symptoms...

Daytime drowsiness increases risk of Alzheimer’s in the elderly

Poor sleep and the risk of dementia go hand in hand, but no one knew which came first. In what researchers say is the first study of its kind, a study published Monday in the...

Boosting brain’s immune cell function may improve Alzheimer’s symptoms

Scientists have known for about five years that mutations in the gene TREM2 increase a person’s risk of developing Alzheimer’s disease. Now, UCLA researchers have shown in mice that boosting levels of the...

Spread of Alzheimer’s proteins shown in healthy people

Using living elderly people, scientists at Maastricht University (UM) and Harvard Medical School in the US city of Boston have succeeded for the first time in figuring out how Alzheimer’s proteins spread inside the brain. Furthermore, the...

Aβ, Then Metabolism, Then Atrophy – In Familial AD, Cascade is Definitive

In the brains of carriers of familial Alzheimer’s disease mutations, Aβ starts accumulating in some regions more than two decades before symptoms appear, metabolism wanes six years later, and the brain begins to shrink about...

Curcumin’s Cognitive Benefits Look Convincing

You may have heard the exciting news about curcumin and its potential for treating Alzheimer’s disease. A recent study by Gary Small and colleagues, published in the American Journal of Geriatric Psychiatry, showed something...

The importance of family history in the onset of Alzheimer’s

You’re about to turn 60, and you’re fretting. Your mother has had Alzheimer’s disease since the age of 65. At what age will the disease strike you? A Canadian study published in JAMA Neurology shows that the...

Women’s Brains Are More Active Than Men

In one of the largest functional brain imaging studies conducted specific brain differences between men and women have been identified by the Amen Clinics using images provided by 9 clinics as published in the Journal of Alzheimer’s...

Molecular markers may ID Alzheimer’s before clinical onset

For young adults with autosomal dominant Alzheimer’s disease (AD), molecular markers can identify changes associated with the disease before clinical onset, according to a study published online Feb. 12 in JAMA Neurology. Yakeel T. Quiroz, Ph.D., from Massachusetts...

Women fare worse than men after a stroke

Women tend to have a tougher time recovering from a stroke than men do, though the reasons aren’t completely clear, researchers say. On average, female stroke survivors reported more limitations in their day-to-day activities than male survivors did,...

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