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Menopause May Be Key Predictor of Alzheimer’s in Women

Alzheimer’s disease does discriminate when it comes to gender. Two-thirds of all cases are women, and in the past it was believed that this was because women tend to live longer than men. However, a...

Obesity linked to higher dementia risk

Obesity is associated with a higher risk of dementia up to 15 years later, finds a new UCL study suggesting that weight management could play a significant role in reducing risk. The findings, published in the International...

Why Some Older Adults Remember Better Than Others

Even among healthy people, a faltering memory is often an expected part of aging – but it’s not inevitable. “Some individuals exhibit remarkable maintenance of memory function throughout late adulthood, whereas others experience significant...

Link between heart health & brain health identified

In the 21st century, global health has seen a drastic shift in the incidence of diseases affecting the human population. In early 2000, the World Health Organization (WHO) reported the top 10 global...

Exercise Builds Brain Health

Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory. But what happens during exercise to trigger these benefits? New UT Southwestern research that mapped...

Thinning Retinas Offer A Clue To Early Alzheimer’s Diagnosis

The earlier we can diagnose Alzheimer’s, the better. This is why scientists are putting so much focus on the human eye. While the exact link between the eye and Alzheimer’s disease is still occluded,...

Aerobics may be a smart workout for your brain at any age

It’s never too late to lace up some sneakers and work up a sweat for brain health, according to a study published in the May 13, 2020, online issue of Neurology, the medical journal of the...

Dementia risk in middle-aged women who have surgically had their ovaries and fallopian tubes removed prior to menopause

More evidence that one of the reasons why more women than men might have Alzheimer’s disease is because of early life endocrine changes. Oophorectomy prior to menopause is associated with...

Gene variant staves off Alzheimer’s in some people

Stanford Medicine researchers have found a gene variant that protects carriers of another gene variant, ApoE4, from developing Alzheimer’s disease — the first demonstration of that beneficial effect. People with a gene variant that puts them at...

Tau Shows Promise as Achilles’ Heel for Alzheimer’s

Alzheimer’s disease has long been characterized primarily by the buildup of two proteins in the brain – beta-amyloid and tau. Decades of focus on beta-amyloid has failed to significantly help patients. So researchers are...

Maternal Risk for Alzheimer’s Disease

Advanced age is the most significant risk factor for late-onset Alzheimer’s disease, and having a parent with the disease is the second. It is estimated that individuals with a first-degree relative with Alzheimer’s disease (AD)...

Researchers design proteins that can be utilized to combat Alzheimer’s

A team of researchers, led by NYU Abu Dhabi Assistant Professor of Biology Mazin Magzoub, has developed small proteins called cell-penetrating peptides (CPPs) that prevent the aggregation of the amyloid-β (Aβ) protein associated with Alzheimer’s disease....

Tau surpasses amyloid for predicting Alzheimer’s-associated neurodegeneration

Utilizing tau PET imaging, new research finds tau to be a more accurate indication for future neurodegeneration, highlighting its potential for precision medicine-based treatment approaches. Amyloid-β has long been the bane of every Alzheimer’s researcher. Often found in...

Ultrasound Therapy Improves the Memory of Alzheimer’s Patients

Brain stimulation therapies have emerged as viable tools to treat a variety of neurological and psychological disorders. They operate by activating or inactivating neural activity in specific regions of the brain and have...

Walking speed at age 45 linked to physical well-being, brain health

Walking speed at age 45 was associated not only with physical health but also with brain health in midlife and even early childhood, according to an NIA-supported study. The findings, published in JAMA Network Open, suggest...

High fat diet impairs new neuron creation in female mice

Sex differences in adult neurogenesis may underlie dementia risk for women. A high fat diet limits the birth and growth of new neurons in adult female, but not male, mice, according to new research published in...

Why are some people resistant to Alzheimer’s?

A new study provides insights on why some people may be more resistant to Alzheimer’s disease than others. The findings may lead to strategies to delay or prevent the condition. The study...

Microglia involved in brain plasticity during sleep

Research from the University of Rochester Medical Center (URMC) suggests that specific immune cells called microglia – which play a crucial role in reorganizing connections between nerve cells, fighting infection, and repairing damage...

Neuroimaging reveals traces of childbirth in the maternal brain

Pregnancy is one of the most dynamic periods in a woman’s life, involving a remarkable potential for brain plasticity that promotes cognitive and emotional adjustments to the newborn. A population-based neuroimaging study provides evidence for a relationship between...

Hormone Therapy Associated With Improved Cognition

A new study demonstrates the benefits of extended estrogen exposure and longer-term hormone therapy in battling cognitive decline. Estrogen has a significant role in overall brain health and cognitive function. That’s why so many...

Male and female mice have different brain cells

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that...

Should Scores on Mild Cognitive Impairment Tests be Adjusted for Sex?

Study Finds More Women, Fewer Men Diagnosed when Sex-specific Scoring Used  Using sex-specific scores on memory tests may change who gets diagnosed with mild cognitive impairment (MCI) by 20 percent, with possibly more women and...

Walking Speed at Early Ages Tied to Cognitive Health

Gait speed at age 45 was a marker of cognitive and physical aging, a longitudinal cohort study showed. Slow gait at age 45 was tied to accelerated biological aging across multiple organ systems and...

Young Adults’ Income Slump May Hike Risk of Middle-Aged Cognitive Issues

A new study suggests that experiencing an annual income drop of 25 percent or more during young adulthood may increase the risk of developing thinking problems and reduced brain health in middle age....

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