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Women Face Greater Challenges With Alzheimer’s Disease Than Men

Women have a harder time of it than men when Alzheimer disease (AD) strikes, according to a multicenter team of investigators from the University of Central Missouri, Medical College of Wisconsin, and University of...

Alzheimer’s discovery points to new approach to treatment

A new study from UBC has found that toxic proteins associated with Alzheimer’s disease produced outside the brain can trigger the disease inside the brain, a discovery that opens the door to a...

Declines in plasticity reveal promising targets for Alzheimer’s

Researchers have identified brain changes linked to memory loss in people with Alzheimer’s disease. The discovery provides a new focus for exploring ways to treat or prevent dementia. The study shows that the brain’s ability to...

A critical link between menopause and Alzheimer’s disease

Alzheimer’s disease, a devastating and irreversible brain disorder that slowly destroys memory and thinking skills, is currently ranked as the sixth-leading cause of death in the United States. For most people with Alzheimer’s, symptoms...

Brain structure make some people resilient to Alzheimer’s

The size, shape and number of dendritic spines in the brain may play a major role in whether someone gets Alzheimer’s disease, according to new research from the University of Alabama at Birmingham. Dendritic...

Do Genes, Sex, and Age Confer a Greater Risk of Developing Alzheimer’s?

A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking,...

Menopause triggers changes in brain that may promote Alzheimer’s

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer’s disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research. The findings, published today...

New insight into how brain cells die in Alzheimer’s & frontotemporal dementia

Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer’s disease, scientists have discovered. Researchers also discovered that LSD1 protein is perturbed in brain samples from...

Middle-aged women with high blood pressure could be at increased risk of dementia

Women who develop high blood pressure in their 40s may be more likely to develop dementia later in life, according to a study published today, 4 October 2017, in the medical journal Neurology. 7,238 people within the...

Study Finds No Evidence of Personality Change Before Dementia Onset

A new comprehensive study from Florida State University (FSU) finds no evidence to support the idea that personality changes begin before the clinical onset of mild cognitive impairment (MCI) or dementia. MCI is an intermediate...

Novel Protein Signals Rapid Hippocampal Atrophy in AD

The presence of TAR DNA-binding protein 43 (TDP-43) in the hippocampus on postmortem examination is associated with increased rates of hippocampal atrophy in patients with Alzheimer’s disease (AD), new research suggests. This association was greatest...

Women with Genetic Risk of Alzheimer’s More Likely than Men to Develop It Between Age 65 and 75

White women whose genes put them at risk of developing Alzheimer’s disease are more likely than white men with similar risk genes to be diagnosed between the ages of 65 and 75, a study drawing on...

Stopping Alzheimer’s Years Before It Starts

Researchers at the Keck School of Medicine of USC are tackling the sixth-leading cause of death in the United States—Alzheimer’s disease—with a new study that intervenes decades before the disease develops. The school is...

AI COULD HELP DIAGNOSE ALZHEIMER’S DISEASE A DECADE EARLIER THAN DOCTORS CAN

A devastating chronic neurodegenerative disease, Alzheimer’s disease (AD) currently affects around 5.5 million people in the United States alone. Causing progressive mental deterioration, it ultimately advances to impact basic bodily functions such as walking and...

Intermittent electrical brain stimulation improves memory

Intermittent electrical stimulation of an area deep inside the brain that degenerates in Alzheimer’s appears to improve working memory, scientists report. Conversely, continuous deep brain stimulation, like the type used for Parkinson’s...

Blood Test Seen to Identify Alzheimer’s with Accuracy

A new type of analysis allowed researchers to use a blood test to help to identify patients with Alzheimer’s in a group of people with neurodegenerative diseases, a study published in the journal...

Moving When Young May Strengthen the Adult Brain

Being active in youth may change the inner workings of brain cells much later in life and sharpen some types of thinking, according to a remarkable new neurological study involving rats. The study...

Women at Risk for Alzheimer’s Face Critical 10-Year Window

Women with a genetic predisposition for Alzheimer’s disease face a 10-year window when they have far greater chances of developing the disease than men with similar genetic risks, a new analysis suggests. That window...

All Signs Point to Tau Tangles as the Culprit in Fading Memory

The two hallmark pathologies of Alzheimer’s disease, amyloid plaques and tau tangles, play different roles in disease progression. Accumulating research suggests that amyloid plaques kick off the disease, precipitating the spread of tau, which then...

CSF and Brain Markers Highlight Different Facets of Dementia

While biomarkers have opened a window onto Alzheimer’s pathogenesis, the view has remained cloudy. At the Alzheimer’s Association International Conference 2017 held July 16-20 in London, the number of biomarker talks was noteworthy, with nearly...

Serotonin may play important role in brain-aging

Recent findings suggested the serotonin system may be an effective target for prevention and treatment of mild cognitive impairment. “Now that we have more evidence that serotonin is a chemical that appears affected early in...

Smell test may identify Alzheimer’s risk

By the time you start losing your memory, it’s almost too late. That’s because the damage to your brain associated with Alzheimer’s disease (AD) may already have been going on for as long as twenty years....

Eye scan reveals Alzheimer’s years before symptoms appear

For decades, the only way to officially diagnose Alzheimer’s disease was by analysing a patient’s brain during a postmortem. More recently, physicians have been able to use positron emission tomography scans of the brains of living people...

The female brain is more active than the male brain

The results of the largest functional brain imaging survey ever conducted suggest female brains are more active than male brains. Scientists surveyed the results of 46,034 brain imaging studies involving single-photon emission computed tomography, or...

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