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Molecular markers may ID Alzheimer’s before clinical onset

For young adults with autosomal dominant Alzheimer’s disease (AD), molecular markers can identify changes associated with the disease before clinical onset, according to a study published online Feb. 12 in JAMA Neurology. Yakeel T. Quiroz, Ph.D., from Massachusetts...

Women fare worse than men after a stroke

Women tend to have a tougher time recovering from a stroke than men do, though the reasons aren’t completely clear, researchers say. On average, female stroke survivors reported more limitations in their day-to-day activities than male survivors did,...

Redefined Alzheimer’s biology has implications for drug design

Despite the 25-year focus on the build-up in brain tissues of one protein, amyloid beta, as the purported origin of Alzheimer’s disease (AD), a new study argues that it is likely triggered instead by the...

Lithium in drinking water could protect against dementia

People exposed to higher levels of lithium in their drinking water are at a reduced risk of dementia, according to a large study published today (Wednesday 23 August 2017) in JAMA Psychiatry. The Danish study combined data...

Alzheimer’s protein may spread like an infection

For the first time, scientists have produced evidence in living humans that the protein tau, which mars the brain in Alzheimer’s disease, spreads from neuron to neuron. Although such movement wasn’t directly observed, the finding...

Increased Midlife Triglyceride Levels Predictive of Alzheimer Disease Pathology

Increased triglyceride levels at midlife are predictive of the presence of β-amyloid (Aβ) and tau pathologies 20 years later in cognitively healthy individuals, according to the results of a recent longitudinal cohort study published...

New Genes Responsible for Alzheimer’s Identified

Researchers report the identification of several new genes responsible for Alzheimer’s disease (AD). The finding is important as the genes include those leading to functional and structural changes in the brain and elevated levels...

How the brain responds to vascular injury

Pericytes, a little-understood type of cell on the brain’s blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina (MUSC) in a January 2nd, 2018 article...

‘Silent Seizures’ May Be A Clue To Memory Loss In Alzheimer’s

Silent seizures” deep within the brain may hold a clue as to what causes memory loss in patients with Alzheimer’s disease, and may help one day lead to new treatments for the 5 million Americans...

Diabetes drug may significantly reverse memory loss

A drug developed for diabetes could be used to treat Alzheimer’s after scientists found it “significantly reversed memory loss” in mice through a triple method of action. The research, published in Brain Research, could bring substantial improvements...

Alzheimer’s Biomarkers

Biomarker, short for biological marker, is simply a measure of a biological process. Blood pressure and body temperature are two common biomarkers. In Alzheimer’s and other forms of dementia, biomarkers are most often tests of bodily fluids including...

2017 Alzheimer’s & Neurodegenerative Research Review

Before the business of 2018 consumes all your brain power, take some time to reflect on the major findings of the last year. We have compiled some of our favorite stories from 2017 into seven major themes, ranging...

Immune cells aid spread of Alzheimer’s protein

One of the hallmarks of Alzheimer’s disease is the formation of clumps, or plaques, of the protein amyloid-β (Aβ) in a person’s brain. Aβ usually starts to aggregate in parts of the...

Gut Microbiome May Modify Neurodegeneration

At the Society for Neuroscience annual meeting, held November 11–15 in Washington, D.C., scientists presented further hints that bacteria in the gut may influence the symptoms and pathology of Alzheimer’s and other neurodegenerative diseases. Tweaking the bacterial profile in...

Physical Health Status Strongly Influences Working Memory

Higher physical endurance, fluid intelligence, and better cognitive function are associated with higher levels of cohesiveness in brain networks involved in working memory (WM), new research shows. On the other hand, suboptimal...

Daily Serving of Leafy Greens May Boost Brain Health

A daily serving of green leafy vegetables may help slow age-related decline in memory and thinking, researchers reported. The prospective study of 960 people (average age 81) from the Memory and Aging Project (MAP)...

Taking clot-prevention drugs for afib may lower risk of dementia

Among people who have atrial fibrillation (afib), those who take anti-clotting medications may be less likely to develop dementia later in life than those who don’t take the drugs, a new study finds. Afib, a disorder...

Researchers Discover Genetic Profile Unique to Dementia With Lewy Bodies

In a discovery that could potentially pave the way for more targeted treatments, researchers announced that dementia with Lewy bodies (DLB) has a unique genetic profile, separate from those of Alzheimer disease (AD) or Parkinson...

Faulty Brain Rhythms In Sleep May Cause Forgetfulness

The young are often envied for their youth and boundless amounts of energy. This is in stark contrast to elderly individuals who become less physically able and tire out much easier. Older individuals...

Oxygen Therapy May Ease Symptoms Of Alzheimer’s

Oxygen therapy, already a form of treatment for a host of conditions, has been found to alleviate symptoms associated with the damage to brain tissue in patients with Alzheimer’s disease, a type of dementia that progressively destroys...

Canola oil may be more harmful than healthful for the brain

Consumption of canola oil is linked to weight gain and declines in memory and learning ability in mice that model Alzheimer’s disease, according to a new study published in the journal Scientific Reports. Canola...

Memory Scores Have Limited Value as Early Alzheimer Disease Screening Tools

Low memory scores are an early marker of amyloid positivity, but have limited value as a screening measure for early Alzheimer’s disease among persons without dementia, according to a study published online in JAMA Psychiatry. Willemijn J....

Women Face Greater Challenges With Alzheimer’s Disease Than Men

Women have a harder time of it than men when Alzheimer disease (AD) strikes, according to a multicenter team of investigators from the University of Central Missouri, Medical College of Wisconsin, and University of...

Alzheimer’s discovery points to new approach to treatment

A new study from UBC has found that toxic proteins associated with Alzheimer’s disease produced outside the brain can trigger the disease inside the brain, a discovery that opens the door to a...

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