As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: October 11, 2013
by Truth Drive:
Early researches have shown that exercise is good for the brain, but now investigators have identified a molecule called irisin that is produced in the brain during endurance exercise and has neuroprotective effects.
Researchers were able to artificially increase the levels of irisin in the blood to activate genes involved in learning and memory.
While it’s known that exercise can boost cognitive function and lessen symptoms of neurological diseases like depression, stroke, and Alzheimer’s disease, the mechanisms underlying these effects are unclear. One important player is thought to be a growth factor named brain-derived neurotrophic factor (BDNF).
Through experiments conducted in mice, investigators led by Dr. Bruce Spiegelman of the Dana-Farber Cancer Institute and Harvard Medical School found that a molecule called FNDC5 and its cleavage product, irisin, are elevated by endurance exercise in the brain and increase BDNF expression.
On the other hand, mice genetically altered to have low irisin levels in the brain had reduced levels of BDNF.
The team also found that raising levels of irisin in the circulation caused the molecule to cross the blood brain barrier, where it increased expression of BDNF and activated genes involved in cognition.
The study is published in the Cell Press journal Cell Metabolism.
For young adults with autosomal dominant Alzheimer’s disease (AD), molecular markers can identify changes associated with the disease before clinical onset, according to a study published online Feb. 12 in JAMA Neurology. Yakeel T. Quiroz, Ph.D., from Massachusetts...
Foods can determine whether someone will suffer from dementia in later years, according to researchers at the Hebrew University of Jerusalem’s Faculty of Agriculture, Food and Environment in Rehovot. A large-scale international study that...
Taking care of someone with Alzheimer’s disease and other forms of dementia is not an easy task. Caregiving is a long-term endeavour that is mentally, emotionally, physically, and financially demanding, and is a role that...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.