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Published on: January 22, 2012
by Daily News & Analysis:
Kiwi researchers are on the verge of developing a blood test, which would help in early diagnosis of Alzheimer’s disease.
According to team leader, Professor Cliff Abrahams, treatments for the disease would perhaps be developed in the near future, but to be useful, they would need to be administered while the disease was in its early stages, before causing considerable brain damage. A blood test that could identify biomarkers for those at risk would contribute to an early diagnosis and aid treatment, Stuff.co.nz reported.
“The expectation is that when such treatments do come on stream — and it is just a matter of time — we will want to be able to give people whatever treatment is developed as early as possible,” said Abrahams. “It’s agreed that the earlier you can diagnose, the better it will be.”
The current ways of detecting the disease in patients include neuropsychological testing and clinical assessment with some of the tests being invasive and expensive. “The attraction of a blood test is simplicity and cost. It can be done in any centre. You don’t need to have access to sophisticated equipment.”
Over the next two months, researchers at the University of Otago would recruit around 80 patients with Alzheimer’s disease and take blood samples. Plasma molecules would then be monitored using biochemical and molecular techniques to spot proteins or other biomarkers that characterize the disease.
The predictive power would then be tested on archived blood samples from previous volunteers, some of whom had since developed Alzheimer’s.
Abrahams hoped that within two to three years, the team would have a verified way of identifying those likely to get Alzheimer’s disease and he believes that there are already some promising leads, putting them ahead of other researchers in the field.
“There is an urgent need. The population with dementia is going to treble in the next 40 years, so it is going to be a massive burden if we can’t solve the problems of early detection and effective therapy,” he added.
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