As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: March 7, 2015
by Michel D’Andrea for SciTech Connect:
Alzheimer’s is primarily a disease of the brain, although there is a correlation between retinal pathology and Alzheimer’s, as patients often exhibit poor vision and other visual signs of impairment.
Diabetes, while an entirely different disease on the surface, is better known for its effect on the eye as well. Detailed comprehensive eye examinations are essential for all diabetic patients and, if left unchecked, diabetic retinopathy could lead to blindness.
Interestingly, the brain and the eye have similar anatomical vascular barrier structures referred to respectively as the blood-brain and blood-retina barriers. Of note is that vascular pathological factors, such as hypertension, stroke, and high cholesterol, are common in both Alzheimer’s and diabetes.
As described in Chapter 14 of the newly released book, Bursting Neurons and Fading Memories: An Alternative Hypothesis for the Pathogenesis of Alzheimer’s Diseases, a dysfunctional vascular barrier can lose its ability to keep restricted vascular components from entering the brain and eye.
For example, compromised blood-retina function through endothelial cell damage is observed before clinical evidence of retinopathy in diabetic patients. Similarly, vascular pathologies in the brain precede the presence of plaques and cognitive impairments in AD mouse transgenic models. Therefore, dysfunctional blood-barrier function could be one of the earliest structural pathological events in these diseases.
The emerging science of epigenetics describes the way our lifestyle and environment influence our gene expression over time. This growing field of research is a hot topic right now because it has radically altered our...
They cleansed the rodents of retired cells. Over...
In 2012, almost one-third of the Canadian population provided care to family members or friends with long-term health conditions, primarily those linked to aging/frailty and forms of dementia. This number will only increase, placing more and...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.