Published on: April 9, 2015
by Conor Kane for Irish Examiner:
Researchers have found that Alzheimer’s patients have “significantly worse” vision than others in their age group, and are more likely to be deficient in key nutrients in the eye.
A multi-disciplinary team from the Vision Research Centre at Waterford Institute of Technology also discovered it is possible to improve the vision of patients with Alzheimer’s by providing supplements which include the carotenoid macular pigment.
The findings have been published in the Journal of Alzheimer’s Disease following funding by the UK-based Howard Foundation.
Future phases of the project, led by Professors John Nolan and Stephen Beatty along with Riona Mulcahy of the age-related care unit at University Hospital Waterford, will follow a cohort of patients with early signs of cognitive decline over a three-year period.
This will be aimed at investigating whether taking specific supplements can arrest the decline in cognitive function, and possibly improve it.
“In the absence of a cure for Alzheimer’s, it is vital that we look at risk factors and establish patterns between Alzheimer’s disease and other conditions,” he said.
“What our research found is that patients with Alzheimer’s disease not only have lower cognition but also considerably poorer vision compared to their peers of the same age without Alzheimer’s.
“Furthermore, we have found that those with Alzheimer’s are significantly lacking in lutein, zeaxanthin, and meso-zeaxanthin. These nutrients are known as dietary carotenoids and at the back of the eye where they are vitally important, they are referred to as macular pigment.”
The researchers wanted to establish whether it was possible to help restore some of the vision lost in people with Alzheimer’s. “Our trials using supplements that are rich in carotenoids found that patients did indeed experience improved vision as their macular pigment was boosted.”
Prof Beatty said it was “particularly exciting” to see clinically meaningful improvements in the eyesight of Alzheimer’s patients who received supplements with carotenoids for six months.
“The research outcomes support the view that the Alzheimer’s patients in the study are well capable of responding to and benefiting from carotenoids but have not had them sufficiently present in their diet.
“At a societal level, this also serves to underline once again the importance of a diet rich in fruit and vegetables in reducing our risk of various debilitating conditions as we get older.”
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