As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: December 29, 2015
As 2015 comes to a close, Healio.com/Psychiatry looked back at the most popular research on Alzheimer’s disease and dementia within the past year.
They include investigations of Alzheimer’s disease and dementia risk factors, potential treatments, new screening tools, and a call for further research in the field.
Vitamin D deficiency increased dementia, Alzheimer’s disease risk
David J. Llewellyn, PhD, of the University of Exeter Medical School in the United Kingdom, and colleagues evaluated 1,658 adults aged 65 years and older without dementia to determine the effect of vitamin D levels on dementia risk. Participants were followed for a mean of 5.6 years.Read more
High antihistamine use among elderly increased risk for dementia, Alzheimer’s disease
Shelly L. Gray, PharmD, MS, of the University of Washington School of Pharmacy, and colleagues conducted a population-based prospective cohort study on participants from the Adult Changes in Thought study. Study participants (median age at enrollment, 74.4 years) were randomly sampled Seattle-area Group Health members recruited from 1994 to 1996. Additional participants were enrolled from 2000 to 2003. Read more
Alzheimer’s disease dementia may be detectable via cognitive tests 18 years prior to diagnosis
To further explore the relation of performance on brief cognitive tests to development of diagnosed Alzheimer’s disease dementia, researchers assessed data from the Chicago Health and Aging Project, a longitudinal, population-based study of health conditions among adults aged 65 years and older. Study participants (n = 2,125) completed cognitive tests approximately every 3 years over an 18-year follow-up period. Fifty-five percent of the study cohort was black. The study was conducted from 1993 to 2012. Read more
New brief dementia screening tool shows comparable accuracy with gold standard
Due to shortcomings of current dementia screening methods, James E. Galvin, MD, MPH developed the Quick Dementia Rating System (QDRS), a 10-item questionnaire that assesses memory and recall, orientation, decision-making and problem solving abilities, activity outside the home, function at home and hobbies, personal hygiene, behavior and personality changes, language and communication abilities, mood, and attention and concentration. The QDRS is completed by a caregiver, family member or friend. Scores range from 0 to 30, with higher scores representing greater cognitive impairment. Read more
Experts: ‘Lifestyle use’ of cognitive enhancing drugs should be investigated
The long-term ‘lifestyle use’ use of cognitive enhancing drugs by healthy people is potentially harmful and should be further investigated by the government, pharmaceutical industry, and national medical organizations, according to a Personal View paper recently published in The Lancet Psychiatry. Read more
Meta-analysis highlights modifiable risk factors for Alzheimer’s disease
In a meta-analysis of 323 studies, researchers identified medical, dietary, biochemical, psychological and lifestyle factors associated with increased and decreased risk for Alzheimer’s disease. Read more
Six goals to close research gap, slow dementia progression
The complex nature of dementia emphasizes the relevance of how care is delivered in a multifactorial approach. One speaker addressed six goals to close the research gap at the Alzheimer’s Disease Research Summit 2015. Read more
Phase 2 study shows resveratrol safe, effective for Alzheimer’s disease
Turner and colleagues conducted a randomized, placebo-controlled, double-blind trial to assess the effect of resveratrol on plasma and cerebrospinal fluid levels of the biomarkers amyloid-beta (Aβ) 42 and Aβ40, and cerebrospinal fluid tau and phospho-tau 181, and on volumetric MRI outcomes. They also evaluated safety and tolerability of resveratrol. Read more
Electromagnetic brain stimulation of an area of the brain known as the hippocampus has improved the memory of older adults with age-related memory loss, in a study published in the journal Neurology. Researchers from Northwestern...
Telling an elderly parent that they need to stop driving and taking away their car keys is one of the most difficult things adult children have to do. But there is something that can be...
Using a machine-learning approach, investigators identified four plasma proteins that correlate with cerebrospinal fluid amyloid-beta-1-42 status; these proteins plus apolipoprotein E4 genotype predicted amyloid positivity. Levels of four blood proteins, when combined with apolipoprotein...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.