As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: October 1, 2012
Can vitamin C and beta-carotene help protect people from dementia? New research from Germany suggests they can. University of Ulm scientists investigated the effect of antioxidants on the pathogenesis of Alzheimer’s disease.
Presented in the Journal of Alzheimer’s Disease, the results indicate that it is possible to influence the pathogenesis of this neurological disorder through the use of dietary antioxidants or even a change in diet. The study was funded in part by the EU’s Seventh Framework Programme (FP7).
Around 700,000 people in Germany are diagnosed as having Alzheimer’s disease. Symptoms include lack of orientation, cognitive decline and absentmindedness, triggered by amyloid beta plaques, degeneration of fibrillae and synapse loss. Evaluating 74 Alzheimer’s patients and 158 healthy controls between the ages of 65 and 90, the researchers discovered that the serum concentration of the antioxidants vitamin C and beta-carotene are much lower in patients with mild dementia than in control persons. It should be noted that the subjects were gender-matched and of the same age. The subjects’ blood and body mass index (BMI) were measured for the study as well.
The researchers said that oxidative stress contributes to the development of Alzheimer’s disease. Oxidative stress constrains the exploitation of oxygen in humans. The team believes that so-called antioxidants could potentially protect the body against neurodegeneration.
For their study, the scientists looked at whether the serum levels of vitamin C, vitamin E, beta-carotene, lycopene and coenzyme Q10 are much lower in the blood of patients suffering from Alzheimer’s.
‘In order to possibly influence the onset and development of Alzheimer’s disease, we need to be aware of potential risk factors,’ said Dr Gabriele Nagel of the University of Ulm.
The team found that the concentration of vitamin C and beta-carotene in the serum of Alzheimer’s patients was much lower than in the blood of control subjects. No such difference was observed between the groups with respect to the other antioxidants (vitamin E, lycopene and coenzyme Q10). The researchers included potential confounding factors like BMI, civil status, education, and consumption of alcohol and tobacco in their statistical analysis.
They found that the storage and preparation of food, and stressors in the patients’ lives could have impacted the findings. ‘Longitudinal studies with more participants are necessary to confirm the result that vitamin C and beta-carotene might prevent the onset and development of Alzheimer’s disease,’ said Dr Nagel.
Depression, stroke and dementia are twice as common in women as in men. Among Alzheimer’s patients, 70 per cent are female. But according to Lynn Posluns, the driving force behind the first “Women’s Brain...
Women are twice as likely as men to develop dementia and almost 70 per cent of new Alzheimer’s patients will be women, yet research has traditionally focused on men. Women’s Brain Health Initiative (WBHI) wants...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.