As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: April 19, 2012
by Brain Posts
Several traditional risk factors have been identified for the future development of Alzheimer’s dementia. These include age, lower premorbid educational level, history of head trauma and family history of Alzheimer’s. However, despite discovery of these risk factors they fail to completely explain the risk of developing Alzheimer’s.
A group of researchers from Dalhousie University in Halifax, Canada recently published a study exploring novel non-traditional factors that might influence risk of dementia and death. They constructed a roster of 19 variables linked to frailty but not previously linked to dementia. These variables included items such as:
A group of over 7,000 elderly Canadian subjects with normal cognitive function at baseline were rated on these 19 frailty variables and were followed for ten years. Risk for death and dementia in the sample were analyzed with attention to the association with the frailty variables.
Individual frailty variables had limited association with risk for death or dementia. However, when combined to produce a frailty index important associations were found. Subjects with higher scores on the frailty index were much more likely to die in the ten-year followup period (65% risk of death in the high index score group compared to only 25% in the low index score group). Additionally, the risk of developing Alzheimer’s disease in the ten-year followup period was elevated by higher frailty index scores (50% risk for higher frailty versus 15% for lower index subjects).
The research group controlled for possible confounding effects of variables noted to be related to dementia, i.e. age and educational status. The effect of a higher frailty index on Alzheimer’s dementia risk persisted after controlling for these variables.
The authors note the potential important clinical and public health implications of their findings. Efforts to identify and treat general medical health conditions in the elderly may reduce the risk for incident Alzheimer’s disease. Future research in the epidemiology of dementia will need to assess and examine the effect of general medical status.
A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking,...
Just because someone has difficulty remembering things, it doesn’t necessarily mean that what they’re experiencing is a symptom of dementia, a new Canadian study says. But if the person is not aware of the...
In the late 1980s, psychologist James Pennebaker developed a form of writing therapy called expressive writing. When you engage in expressive writing, you write about your deepest thoughts and feelings without concern for...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.