Published on: May 10, 2015
by Medical XPress:
In the white matter of the brain in particular, large differences can be measured between the brains of people with Alzheimer’s disease and those with the behavioural variant frontotemporal dementia.
Neuropsychologist Christiane Möller used advanced image analysis techniques on MRI brain scans from dementia patients in an early stage of the disease. She will defend her doctoral research on 1 May at the VU University Medical Centre. Her research was funded by the NWO’s National Initiative Brain & Cognition.
Alzheimer’s disease and the behavioural variant of frontotemporal dementia (FTD) are the two most commonly occurring types of dementia at a young age. Medical specialists still find it difficult to make a distinction between the two types of disease at an early stage of the illness. Using existing imaging techniques the difference is often not visible to the naked eye on scans.
Möller used advanced analysis methods that can measure brain damage not yet visible to the human eye. “At a group level the diseases were found to exhibit large differences in the white matter of the brain in particular. In frontotemporal dementia there is a lot of damage to the white matter of the brain in the foremost parts of the brain, whereas in the brains of people with Alzheimer’s disease no damage could be measured compared with FTD. A combination of different analysis methods made the distinction even clearer still.”
The aim of the research was to detect changes in the brain as early as possible and to determine if there were differences in the brain between the two types of dementia. “For drug development in particular, a good diagnosis is a prerequisite”, says Möller. The VU University Medical Center carried out the study together with Leiden University Medical Center and the Erasmus Medical Center in Rotterdam. This research falls under the programme ‘Brain & Cognition: societal innovation’ and is funded by the National Initiative Brain & Cognition, a unit of NWO.
Although it’s great to celebrate the big achievements, it’s also important to celebrate the small wins.
Women are affected by Alzheimer’s disease and other forms of dementia in much larger numbers than men. Approximately two-thirds of Canadians and Americans living with dementia are women. Why are women disproportionately affected? Partly, it...
Your brain is affected by what you eat! Join us Thurs. Jan. 21st for an engaging culinary virtual event. Featuring Special Guest MARK McEWAN Celebrity Chef and Restauranteur With...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.