As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: July 13, 2012
Activity lingers longer in certain areas of the brain in those with Alzheimer’s than it does in healthy people, Mayo Clinic researchers who created a map of the brain found. The results suggest varying brain activity may reduce the risk of Alzheimer’s disease.
The study, “Non-stationarity in the “Resting Brain’s” Modular Architecture,” was presented at the Alzheimer’s Association International Conference and recently published in the journalPLoS One.
Researchers compared brain activity to a complex network, with multiple objects sharing information along pathways.
“Our understanding of those objects and pathways is limited,” says lead author David T. Jones, M.D. “There are regions in the brain that correspond to those objects, and we are not really clear exactly what those are. We need a good mapping or atlas of those regions that make up the network in the brain, which is part of what we were doing in this study.”
Researchers examined 892 cognitively normal people taking part in the Mayo Clinic Study of Aging, and set out to create an active map of their brains while the people were “at rest,” not engaged in a specific task. To do this, they employed task-free, functional magnetic resonance imaging to construct an atlas of 68 functional regions of the brain, which correspond to the cities on the road map.
Researchers filled in the roads between these regions by creating dynamic graphic representations of brain connectivity within a sliding time window.
This analysis revealed that there were many roads that could be used to exchange information in the brain, and the brain uses different roads at different times. The question to answer then, said Dr. Jones, is whether or not Alzheimer’s patients used this map and these roads in a different way than their healthy peers.
“What we found in this study was that Alzheimer’s patients tended to spend more time using some roads and less time using other roads, biasing one over the other,” he says.
While more research is needed, the researchers say one implication is that how we use our brains may protect us from Alzheimer’s. Dr. Jones says exercise, education, and social contacts may help balance activity in the brain.
“Diversifying the mental space that you explore may actually decrease your risk for Alzheimer’s,” he says.
This work was supported by the National Institute on Aging, the Alexander Family Alzheimer’s Disease Research Professorship of the Mayo Foundation, and Alzheimer’s Association New Investigator grant.
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has...
Sometimes, the hardest part of living with a mental illness isn’t the symptoms, or the management — it’s dealing with stigma from other people. And unfortunately, many people who live with mental illness face stigma...
The root cause of behavioural outbursts in someone with Alzheimer’s disease is mostly due to the decline in the person’s language and communication skills. Outbursts also can be caused by an unmet need or needs. The affected...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.