As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: June 8, 2012
by Medical XPress:
The drugs commonly used to treat memory loss in Alzheimer’s patients can make bones stronger, according to a recent study led by Faleh Tamimi, assistant professor at McGill University’s Faculty of Dentistry. The findings, published in Journal of Bone and Mineral Research and highlighted in Nature Reviews: Endocrinology, could help further research into the idea that bone strength is controlled centrally within the brain.
Two drugs frequently used to treat Alzheimer disease (AD), donepezil and rivastigmine, are known to stimulate a group of neurons in the brain that play a major role in maintaining memory. While these drugs have been widely used in the treatment of AD and other forms of dementia since the mid-1990s, their potential effect on bone biology had not been explored.
Recent research indicated that certain neurons can regulate bone metabolism and that their damage results in weaker bones. But little was known about the potential that increased activity by these neurons might have on bone. The McGill-led team determined that the use of donepezil and rivastigmine, two drugs that in theory could increase the activity of bone-regulating neurons, is associated with a beneficial effect on bone strength and a decreased risk of hip fracture in Alzheimer’s patients.
The researchers studied Alzheimer’s patients, aged 75 or older, who were treated at a single hospital in Spain. Eighty recorded cases of hip fractures were compared with 2,178 patients without hip fracture (control group). The study showed that patients who were receiving donepezil and rivastigmine were associated with a lower risk of hip fracture.
“These findings improve our understanding of bone disease and open a new therapeutic window for the treatment of osteoporosis,” explained Prof. Tamimi. “An added value of this discovery is that the drugs we found to be beneficial for preventing hip fractures are readily available in pharmacies. Even though more tests are required to confirm our findings, the fact that donepezil and rivastigmine have been proven safe will facilitate the translation of our discovery into clinical application for treating patients suffering from osteoporosis.”
It has long been known that vitamin D – often referred to as the “sunshine vitamin” – is one of the most essential vitamins for our overall health because it regulates calcium in the body...
SWEAT IT OUT Sauna bathing, a form of passive heat therapy, is a traditional activity in Finland that is primarily used for relaxation purposes and is becoming increasingly common in many other populations. The typical...
Has anyone ever suggested that you take a deep breath to help you relax when you are feeling anxious or stressed? That advice has roots in the wisdom of ancient yogic teachings. Breathing – that...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.