As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: March 29, 2015
by Elizabeth Gough-Gordon for MPR:
Memory problems associated with Alzheimer’s disease may one day be reversed with targeted immunotherapy, according to a new study appearing in theJournal of Neuroscience.
Scientists from the University of Texas Medical Branch at Galveston had previously found that anti-tau oligomer immunotherapy reduced levels of toxic tau oligomers and reversed memory deficits in an animal model of Alzheimer’s disease.
In the current research of passive immunotherapy with tau oligomer-specific monoclonal antibody, the removal of tau oligomers also reversed memory deficits and accelerated plaque deposition in the brains of mice. Unlike other tau immunotherapy treatments, this one only targeted the toxic oligomer form of tau, leaving the normal tau to carry out typical functions.
However, amyloid beta oligomer levels were also reduced with the immunotherapy, which indicates that the effects of amyloid beta may also be dependent on the presence of toxic forms of tau.
These results support the targeting of tau oligomers with immunotherapy as a potential treatment for Alzheimer’s disease. The removal of tau oligomers with immunotherapy could also decrease the harmful effects of amyloid beta and mediate memory problems.
It is a devastating omission that may have undercut years of work by brilliant researchers from around the world. Millions of dollars and countless hours have been spent investigating dementia. But in the view of...
A stroll through the Dutch community of De Hogeweyk is a journey to what could be the future of dementia care. Located within the small town of Weesp, just outside of Amsterdam, De Hogeweyk is...
Intimate-partner violence (IPV) is a pattern of physical and/or sexual violence inflicted by an intimate or ex-intimate partner. Global estimates published by the World Health Organization indicate that about 1 in 3 women have experienced...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.