As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: October 20, 2019
by The North American Menopause Society:
A new study demonstrates the benefits of extended estrogen exposure and longer-term hormone therapy in battling cognitive decline.
Estrogen has a significant role in overall brain health and cognitive function. That’s why so many studies focused on the prevention of cognitive decline consider the effect of reduced estrogen levels during the menopause transition. A new study suggests a cognitive benefit from a longer reproductive window complemented with hormone therapy.
Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Because women comprise two-thirds of the 5.5 million cases of Alzheimer disease in the United States, researchers have long suspected that sex-specific factors such as estrogen may contribute to women’s increased risk for the disease. Multiple studies have previously suggested a role for estrogen in promoting memory and learning.
In this newest study involving more than 2,000 postmenopausal women, researchers followed participants over a 12-year period to examine the association between estrogen and cognitive decline. More specifically, they focused on the duration of a woman’s exposure to estrogen, taking into account such factors as time of menarche to menopause, number of pregnancies, duration of breastfeeding, and use of hormone therapy.
The researchers concluded that a longer duration of estrogen exposure is associated with better cognitive status in older adult women. Furthermore, they documented that these beneficial effects are extended with the use of hormone therapy, especially in the oldest women in the sample. Women who initiated hormone therapy earlier showed higher cognitive test scores than those who started taking hormones later, providing some support for the critical window hypothesis of hormone therapy.
Study results appear in the article “Lifetime estrogen exposure and cognition in late life: The Cache County Study.” “Although the assessment of the risk-to-benefit balance of hormone therapy use is complicated and must be individualized, this study provides additional evidence for beneficial cognitive effects of hormone therapy, particularly when initiated early after menopause.
This study also underscores the potential adverse effects of early estrogen deprivation on cognitive health in the setting of premature or early menopause without adequate estrogen replacement,” says Dr. Stephanie Faubion, NAMS medical director.
As awareness of Alzheimer’s and dementia continues to grow; and, as the population ages the number of people searching for online memory tests continues to grow fast.In discussions with Universities and memory centers...
Doctors are not good at diagnosing Alzheimer’s and neither are spouses or children. Previously I wrote — What Was The First Sign of Alzheimer’s Disease in Your Case? In that article I asked Alzheimer’s caregivers to...
New research finds that high cholesterol and high blood pressure not only put patients at risk for heart disease but are also risk factors for early memory loss and other cognitive problems. In the study, participants...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.