Published on: June 18, 2015
by DNA India:
A new study reveals longevity hormone is lower in stressed and depressed women.
Women under chronic stress have significantly lower levels of klotho, a hormone that regulates ageing and enhances cognition, researchers at UC San Francisco have found in a study comparing mothers of children on the autism spectrum to low-stress controls.
The researchers found that the women in their study with clinically significant depressive symptoms had even lower levels of klotho in their blood than those who were under stress but not experiencing such symptoms. The study is the first to show a relationship between psychological influences and klotho, which performs a wide variety of functions in the body.
Lead author Aric Prather said that the findings suggest that klotho, which they now know is very important to health, could be a link between chronic stress and premature disease and death, adding that since the study is observational, they cannot say that chronic stress directly caused lower klotho levels, but the new connection opens avenues of research that converge upon ageing, mental health, and age-related diseases.
Scientists know from their work in mice and worms that, when klotho is disrupted, it promotes symptoms of ageing, such as hardening of the arteries and the loss of muscle and bone, and when klotho is made more abundant, the animals live longer.
Senior author Dena Dubal said that chronic stress transmits risk for bad health outcomes in ageing, including cardiovascular and Alzheimer’s disease, adding that it will be important to figure out if higher levels of klotho can benefit mind and body health as women age. Dubal added that if so, therapeutics or lifestyle interventions that increase the longevity hormone could have a big impact on people’s lives.
The study is published in Translational Psychiatry.
Although it’s great to celebrate the big achievements, it’s also important to celebrate the small wins.
Women are affected by Alzheimer’s disease and other forms of dementia in much larger numbers than men. Approximately two-thirds of Canadians and Americans living with dementia are women. Why are women disproportionately affected? Partly, it...
Your brain is affected by what you eat! Join us Thurs. Jan. 21st for an engaging culinary virtual event. Featuring Special Guest MARK McEWAN Celebrity Chef and Restauranteur With...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.