Published on: May 1, 2008
by Catharine Paddock, PhD for Medical News Today:
New research from France suggests that men and women have different risks for mild cognitive impairment (MCI) and progression to dementia. The researchers suggest stroke is a primary risk factor for men, and depression for women.
The study is the work of Dr Karen Ritchie, of the Université de Montpellier and La Colombière Hospital in Montpellier, and colleagues, and is published online ahead of print today, 1st May, in the Journal of Neurology, Neurosurgery, and Psychiatry.
The researchers carried out a prospective community based study over four years of 6,892 men and women aged 65 and over living in three cities in France.
None of the participants had dementia when enrolled on the study (baseline), and they all underwent cognitive performance tests, clinical diagnosis for dementia, and evaluation of clinical and environmental risk factors at baseline, year 2, and year 4 of the study.
The results showed that:
The researchers concluded that: “Men and women have different risk profiles for both MCI and progression to dementia.”
They recommended that interventions should: “Focus principally on risk of stroke in men and depressive symptomatology and use of anticholinergic medication in women.”
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