As the largest resource of information specific to women's brain health, we are sure you will find what you are looking for, and promise that you will discover new information.
Published on: May 29, 2012
by Ken Grogan for Pharma Times:
Lundbeck says its investigational Alzheimer’s disease drug Lu AE58054 has met its primary endpoint in a mid-stage study.
The Phase II trial was conducted in 278 patients suffering from moderate Alzheimer’s and Lu AE58054 was administered as add-on to Eisai/Pfizer’s blockbuster dementia drug Aricept (donepezil). The Danish drugmaker’s treatment plus donepezil demonstrated significant improvements in cognitive function in Alzheimer’s disease compared to placebo plus donepezil.
Lundbeck noted that secondary endpoints, including measures of global status and activities of daily living also showed positive trends with the addition of Lu AE58054, compared with patients who only received Aricept. The new drug was also considered to be well tolerated at the selected dose.
Head of R&D, Anders Gersel Pedersen, said the results are very encouraging “and we are now evaluating how to best proceed with the development of Lu AE58054”. The firm is looking at a major pivotal clinical programme “potentially including development and commercial partnerships”.
Lu AE58054 is a novel, selective 5HT6 receptor antagonist with a different mechanism of action than currently-available Alzheimer’s medications.
Source: http://www.pharmatimes.com/Article/12-05-29/Lundbeck_Alzheimer_s_drug_impresses_in_Phase_II.aspx
Picture Source: WebMD
It is a devastating omission that may have undercut years of work by brilliant researchers from around the world. Millions of dollars and countless hours have been spent investigating dementia. But in the view of...
A stroll through the Dutch community of De Hogeweyk is a journey to what could be the future of dementia care. Located within the small town of Weesp, just outside of Amsterdam, De Hogeweyk is...
Intimate-partner violence (IPV) is a pattern of physical and/or sexual violence inflicted by an intimate or ex-intimate partner. Global estimates published by the World Health Organization indicate that about 1 in 3 women have experienced...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.
