Published on: February 2, 2014
by ANI News:
A chemical that is found in fruits and vegetables from strawberries to cucumbers apparently stops memory loss that accompanies Alzheimer’s disease in mice, a new study has claimed.
Scientists at the Salk Institute for Biological Studies have discovered in experiments on mice which normally develop Alzheimer’s symptoms less than a year after birth, that a daily dose of the compound—-a flavonol called fisetin—-prevented the progressive memory and learning impairments.
The drug, however, did not alter the formation of amyloid plaques in the brain, accumulations of proteins which are commonly blamed for Alzheimer’s disease. The new finding suggests a way to treat Alzheimer’s symptoms independently of targeting amyloid plaques.
“We had already shown that in normal animals, fisetin can improve memory,” Pamela Maher, a senior staff scientist in Salk’s Cellular Neurobiology Laboratory who led the new study, said.
“What we showed here is that it also can have an effect on animals prone to Alzheimer’s,” she said.
More than a decade ago, Maher discovered that fisetin helps protect neurons in the brain from the effects of aging. She and her colleagues have since—-in both isolated cell cultures and mouse studies—-probed how the compound has both antioxidant and anti-inflammatory effects on cells in the brain. Most recently, they found that fisetin turns on a cellular pathway known to be involved in memory.
“What we realized is that fisetin has a number of properties that we thought might be beneficial when it comes to Alzheimer’s,” Maher said.
The research is published in the journal Aging Cell.
In a new study, University of Nebraska–Lincoln sociologist Marc A. Garcia explored how educational attainment can benefit cognitive health in later life, and whether there are differences in its benefits among minorities. Garcia and his co-authors...
A genetic variation in some people may be associated with cognitive decline that can’t be explained by deposits of two key proteins associated with Alzheimer’s disease, amyloid β and tau, according to a study...
As 2020 drags on and the Covid-19 pandemic continues to ravage the world, the number of people reporting mental health issues, including anxiety, depression and stress, has skyrocketed. According to recent data, symptoms of anxiety and...
The material presented through the Think Tank feature on this website is in no way intended to replace professional medical care or attention by a qualified practitioner. WBHI strongly advises all questioners and viewers using this feature with health problems to consult a qualified physician, especially before starting any treatment. The materials provided on this website cannot and should not be used as a basis for diagnosis or choice of treatment. The materials are not exhaustive and cannot always respect all the most recent research in all areas of medicine.